Table 2.

Summary of automated hippocampal segmentation in R-TN and control subjects (* p < .05, ** p < .01).

Subfield	Side	Mean volume R-TN (mm3)	Mean volume Control (mm3)	Difference (mm3)	Post-hoc P-value	Significance
Whole hippocampus	R	3308.57	3676.00	−367.42	0.0024	**
	L	3260.83	3529.70	−268.86	0.0557
GC-ML-DG	R	291.06	329.98	−38.92	0.0012	**
	L	277.90	313.62	−35.72	0.0096	**
CA4	R	252.04	281.29	−29.25	0.0046	**
	L	240.07	268.42	−28.35	0.0204	*
CA2/CA3	R	212.94	232.79	−19.84	0.0767
	L	193.78	208.54	−14.76	0.3607
CA1	R	607.34	692.85	−85.51	0.0014	**
	L	591.73	655.47	−63.73	0.0145	*
Subiculum	R	401.66	440.86	−39.21	0.0289	*
	L	409.81	439.00	−29.19	0.1641
Presubiculum	R	270.94	297.07	−26.13	0.0367	*
	L	289.63	306.41	−16.78	0.4390
Parasubiculum	R	58.66	58.49	0.17	>0.9999
	L	63.02	58.28	4.74	0.7317
ML-HP	R	545.48	609.67	−64.19	0.0033	**
	L	535.61	587.12	−51.51	0.0196	*
Fimbria	R	77.70	89.93	−12.24	0.2470
	L	75.57	85.95	−10.38	0.2734
Hippocampal tail	R	535.45	579.08	−43.63	0.1963
	L	529.79	547.57	17.78	>0.9999
Hippocampal fissure	R	142.60	144.24	−1.64	>0.9999
	L	139.73	134.68	5.05	>0.9999
HATA	R	55.31	63.98	−8.67	0.0052	**
	L	53.93	59.34	−5.41	0.1459

Subfield volume difference calculated as: VOI_adj of R-TN - ipsilateral VOI_adj of matched control.

Abbreviations: GC-ML-DG: granule cell and molecular layer of the dentate gyrus; CA: cornu ammonis; ML-HP: molecular layer of hippocampus proper; HATA: hippocampal amygdala transition area.