Fig. 2.

Key characteristics of basket trial, umbrella trial, and platform trial definitions. Theree were 35 definitions of basket trials identified, 26 umbrella trial definitions and 25 for platform trial definitions. These different definitions are summarized based on the number of interventions, diseases, and biomarkers involved are illustrated in the left panel (2a), and features of trial designs included in these definitions are mentioned in the right panel (2b). Basket trials are illustrated in color blue, color red for umbrella trials, and color green for platform trials. . (For interpretation of the references to color in this figure legend, the reader is referred to the Web version of this article.)