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. 2019 Jul 9;9:9911. doi: 10.1038/s41598-019-46303-8

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Principal coordinate plots of weighted Bray-Curtis beta diversity distances across all samples collected in the study. (A) Samples colored by body or ISS surface site; The permanova p-value and R² using body site as the independent variable is shown. (B) Human microbiome samples colored by astronaut identifier. Each microbiome is represented with a different symbol. Permanova p-value and R2 using astronaut identifier as the independent variable and stratifying by body site are indicated.