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. 2019 Jul 9;9:9952. doi: 10.1038/s41598-019-46346-x

Figure 3.

Figure 3

Ryuvidine inhibition of KDM5A was measured by MALDI-TOF/MS methods. Ryuvidine inhibition of KDM5A in the presence of 2-OG was evaluated. Levels of H3K4me3 (me3), H3K4me2 (me2) and H3K4me1 (me1) were measured by MALDI-TOF/MS. H3K4me3 at reaction time 0 min was defined as 100%. Data are presented as means ± SD (n = 3).