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. 2019 Jun 19;8(6):873. doi: 10.3390/jcm8060873

Table 3.

Procedure of Trefle® tissue acquisition and POCS-guided forceps biopsy for differentiating extrahepatic cholangiocarcinoma from benign biliary disease.

Trefle®
(n = 14)
POCS
(n = 20)
p Value
Procedure time, minutes 92.0 (57–129) 85.5 (34–170) 0.766 *1
EST or precut papillotomy (previous/with/without) 1/3/10 5/15/0 <0.001 *2
Number of biopsy, times 2 (1–6) 3 (2–9) 0.0498 *1

Values are presented as number or median (range). Abbreviations: POCS, peroral cholangioscopy; EST, endoscopic sphincterotomy. *1 p value: Mann–Whitney U test. *2 p value: Chi-square test.