. 2019 Apr 3;9(2):32. doi: 10.3390/life9020032

Table 7.

Metalloenzymes involved in energy metabolism in heterocysts.

Pathway	Enzyme	Protein(s)	Cofactor(s)	Metal ^†
Glycolysis	Fructose-1,6-bisphosphate aldolase	FbaA (FBA; All4563 ^‡)	Catalytic Zn²⁺ center	1 Zn²⁺
Glycolysis	Fructose-1,6-bisphosphate aldolase	FbaA (FBA; All4563 ^‡)	Structural Zn²⁺ center	1 Zn²⁺
Pyruvate metabolism	Pyruvate:ferredoxin (flavodoxin) oxidoreductase	NifJ (PFOR; Alr2803 ^‡)	3 × [4Fe–4S] clusters	12 Fe
Pyruvate metabolism	Pyruvate:ferredoxin (flavodoxin) oxidoreductase	NifJ (PFOR; Alr2803 ^‡)	Thiamine pyrophosphate	–
Krebs cycle	Aconitase (aconitate hydratase)	AcnB (All1267 ^‡)	Catalytic [4Fe–4S] cluster	4 Fe

^† Charge is not given for Fe as it varies with the oxidation state during enzymatic catalysis. ^‡ Specific examples in the strain Anabaena sp. PCC 7120.