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. 2019 Jun 21;8(6):890. doi: 10.3390/jcm8060890

Figure 4.

Figure 4

Effects of oltipraz on the expression of nuclear factor erythroid derived-2-related factor 2 (Nrf2), heme oxygenase 1 (HO-1) and NAD(P)H:quinone oxidoreductase 1 (NQO1) in the spinal cord of the CCI-injured mice. The relative protein levels of (A) Nrf2, (B) HO-1, and (C) NQO1 on the ipsilateral side of the spinal cord in the CCI-injured mice treated with oltipraz (OLT) or vehicle are represented. The sham-operated mice (SHAM) treated with vehicle were used as controls. (D) Representative examples of blots for Nrf2 (100 kDa), HO-1 (32 kDa), NQO1 (28 kDa) and GAPDH (37 kDa). Protein levels are expressed relative to GAPDH levels. In all panels, * denotes significant differences vs. sham-operated mice treated with vehicle and + denotes significant differences vs. CCI-injured vehicle-treated mice (p < 0.05; one-way ANOVA followed by the SNK test). Results are presented as the mean ± SEM; n = 5 samples per experimental group.