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. 2019 Apr 27;9(2):e87415. doi: 10.5812/aapm.87415

Table 2. Operative Details of Patients Before, During, and After the Procedure in the Study Groupsa.

Variable Etomidate, N = 25 Midazolam, N = 39 Propofol, N = 34 P Value
Before Surgery
Pulse rate 75.1 ± 15.2 76.7 ± 15.4 73.6 ± 10.1 0.917
Blood pressure
Systolic 154.6 ± 18.5 150.6 ± 22.9 157.7 ± 20.1 0.35
Diastolic 88.8 ± 8.9 84.6 ± 13.1 90.8 ± 10.6 0.63
Mean arterial blood pressure 109.8 ± 8.8 106.3 ± 14.2 112.8 ± 12 0.087
Arterial oxygen saturation 95.4 ± 2.4 94.6 ± 5.3 95.3 ± 2.5 0.659
During Surgery
Ramsay score 0.41
1 1 (4) 5 (12.8) 1 (2.9)
2 1 (4) 3 (7.7) 3 (8.8)
3 9 (36) 7 (17.9) 7 (20.6)
4 14 (56) 24 (61.5) 23 (67.6)
Pulse rate 71.1 ± 13.6 70.7 ± 10.4 69.9 ± 11.2 0.911
Blood pressure
Systolic 155.1 ± 22.0 136 ± 18.5 145.1 ± 19.7 0.001
Diastolic 91.1 ± 9.4 78.2 ± 11.7 84.8 ± 11.6 0.000
Mean arterial blood pressure 111.6 ± 12.2 97.2 ± 12.8 104.6 ± 13.3 0.000
Arterial oxygen saturation 97.2 ± 2.8 96.7 ± 5.7 97.2 ± 2.2 0.807
After Surgery and Recovery
Recovery time 12 (5 - 24) 20 (5 - 40) 5 (5 - 10) 0.04
Pulse rate 66.8 ± 13 68.5 ± 12.4 69.4 ± 11.7 0.713
Blood pressure
Systolic 143.4 ± 24.3 129 ± 20.8 140.1 ± 18.7 0.016
Diastolic 85.8 ± 14.1 74.1 ± 13.1 82.2 ± 11.7 0.001
Mean arterial blood pressure 105.8 ± 17.3 92.1 ± 14.7 101.2 ± 13 0.001
Arterial oxygen saturation 98 ± 1.4 95.4 ± 11.0 97.9 ± 3.5 0.245
Anesthetic complications
Dizziness 0 (0) 1 (2.6) 0 (0) 0.89
Restlessness 2 (8) 4 (10.26) 1 (2.9) 0.47
Vomiting 0 (0) 0 (0) 0 (0) 0.48
Nausea 13 (52) 2 (5.2) 0 (0) < 0.001
Hypoxemia 1 (4) 0 (0) 2 (5.8) 0.61
Bradycardia 8 (32) 10 (26) 7 (20.6) 0.33
Tachycardia 3 (12) 2 (3.2) 1 (2.9) 0.67
Hypotension 5 (20) 13 (33.3) 11 (32.35) 0.47
Sedation adverse event 0.96
Aspiration 0 (0) 0 (0) 0 (0)
Laryngospasm 0 (0) 0 (0) 0 (0)
Intubation 0 (0) 0 (0) 0 (0)
Hospitalization 0 (0) 0 (0) 0 (0)
Mortality 0 (0) 0 (0) 0 (0)

aValues are presented as mean ± SD or median (range) and No. (%).