Table 2. Operative Details of Patients Before, During, and After the Procedure in the Study Groupsa.
Variable | Etomidate, N = 25 | Midazolam, N = 39 | Propofol, N = 34 | P Value |
---|---|---|---|---|
Before Surgery | ||||
Pulse rate | 75.1 ± 15.2 | 76.7 ± 15.4 | 73.6 ± 10.1 | 0.917 |
Blood pressure | ||||
Systolic | 154.6 ± 18.5 | 150.6 ± 22.9 | 157.7 ± 20.1 | 0.35 |
Diastolic | 88.8 ± 8.9 | 84.6 ± 13.1 | 90.8 ± 10.6 | 0.63 |
Mean arterial blood pressure | 109.8 ± 8.8 | 106.3 ± 14.2 | 112.8 ± 12 | 0.087 |
Arterial oxygen saturation | 95.4 ± 2.4 | 94.6 ± 5.3 | 95.3 ± 2.5 | 0.659 |
During Surgery | ||||
Ramsay score | 0.41 | |||
1 | 1 (4) | 5 (12.8) | 1 (2.9) | |
2 | 1 (4) | 3 (7.7) | 3 (8.8) | |
3 | 9 (36) | 7 (17.9) | 7 (20.6) | |
4 | 14 (56) | 24 (61.5) | 23 (67.6) | |
Pulse rate | 71.1 ± 13.6 | 70.7 ± 10.4 | 69.9 ± 11.2 | 0.911 |
Blood pressure | ||||
Systolic | 155.1 ± 22.0 | 136 ± 18.5 | 145.1 ± 19.7 | 0.001 |
Diastolic | 91.1 ± 9.4 | 78.2 ± 11.7 | 84.8 ± 11.6 | 0.000 |
Mean arterial blood pressure | 111.6 ± 12.2 | 97.2 ± 12.8 | 104.6 ± 13.3 | 0.000 |
Arterial oxygen saturation | 97.2 ± 2.8 | 96.7 ± 5.7 | 97.2 ± 2.2 | 0.807 |
After Surgery and Recovery | ||||
Recovery time | 12 (5 - 24) | 20 (5 - 40) | 5 (5 - 10) | 0.04 |
Pulse rate | 66.8 ± 13 | 68.5 ± 12.4 | 69.4 ± 11.7 | 0.713 |
Blood pressure | ||||
Systolic | 143.4 ± 24.3 | 129 ± 20.8 | 140.1 ± 18.7 | 0.016 |
Diastolic | 85.8 ± 14.1 | 74.1 ± 13.1 | 82.2 ± 11.7 | 0.001 |
Mean arterial blood pressure | 105.8 ± 17.3 | 92.1 ± 14.7 | 101.2 ± 13 | 0.001 |
Arterial oxygen saturation | 98 ± 1.4 | 95.4 ± 11.0 | 97.9 ± 3.5 | 0.245 |
Anesthetic complications | ||||
Dizziness | 0 (0) | 1 (2.6) | 0 (0) | 0.89 |
Restlessness | 2 (8) | 4 (10.26) | 1 (2.9) | 0.47 |
Vomiting | 0 (0) | 0 (0) | 0 (0) | 0.48 |
Nausea | 13 (52) | 2 (5.2) | 0 (0) | < 0.001 |
Hypoxemia | 1 (4) | 0 (0) | 2 (5.8) | 0.61 |
Bradycardia | 8 (32) | 10 (26) | 7 (20.6) | 0.33 |
Tachycardia | 3 (12) | 2 (3.2) | 1 (2.9) | 0.67 |
Hypotension | 5 (20) | 13 (33.3) | 11 (32.35) | 0.47 |
Sedation adverse event | 0.96 | |||
Aspiration | 0 (0) | 0 (0) | 0 (0) | |
Laryngospasm | 0 (0) | 0 (0) | 0 (0) | |
Intubation | 0 (0) | 0 (0) | 0 (0) | |
Hospitalization | 0 (0) | 0 (0) | 0 (0) | |
Mortality | 0 (0) | 0 (0) | 0 (0) |
aValues are presented as mean ± SD or median (range) and No. (%).