Table 1.
Characteristics of the patients with obesity and type 2 diabetes mellitus before (M0) and 3 months (M3) and 1 year (M12) after sleeve gastrectomy.
| N = 18 | M0 | M3 | M12 | p Value # |
|---|---|---|---|---|
| Body weight (kg) | 99.4 ± 19.0 | 79.0 ± 15.4 | 75.1 ± 17.0 | <0.001 |
| BMI (kg/m2) | 35.6 ± 5.1 | 28.4 ± 4.3 | 27.0 ± 4.2 | <0.001 |
| Waist circumference (cm) | 108.9 ± 11.0 | 92.1 ± 10.3 | 86.9 ± 12.7 | <0.001 |
| Excess weight loss (%) | 56.4 ± 19.6 | 68.7 ± 20.8 | <0.001 | |
| ABSI | 0.078 ± 0.005 | 0.074 ± 0.003 | 0.073 ± 0.006 | <0.05 |
| Laboratory data | ||||
| Creatinine (mg/dL) | 0.97 ± 0.62 | 1.00 ± 0.89 | 0.94 ± 0.55 | NS |
| Fasting blood glucose (mg/dL) | 142.1 ± 59.2 | 93.4 ± 8.9 | 91.0 ± 15.1 | 0.05 |
| HbA1c (% IFCC) | 8.2 ± 1.7 | 6.0 ± 0.5 | 5.8 ± 0.5 | 0.001 |
| C-peptide (ng/mL) | 3.8 ± 1.6 | 2.1 ± 1.2 | 2.0 ± 0.5 | <0.01 |
| Insulin (mU/L) | 12.7 ± 6.5 | 5.3 ± 3.0 | 4.5 ± 2.7 | 0.001 |
| Albumin (g/dL) | 4.5 ± 0.3 | 4.4 ± 0.3 | 4.3 ± 0.3 | <0.01 |
| ALT (U/L) | 54.9 ± 55.0 | 18.5 ± 9.8 | 15.6 ± 5.8 | <0.05 |
| AST (U/L) | 34.7 ± 30.6 | 18.5 ± 7.8 | 18.1 ± 7.8 | NS |
| Alk-p (U/L) | 63.1 ± 17.0 | 65.3 ± 18.4 | 65.0 ± 20.8 | NS |
| γ-GT (U/L) | 54.0 ± 42.9 | 27.5 ± 34.3 | 19.0 ± 8.7 | <0.01 |
| Total cholesterol (mg/dL) | 187.1 ± 39.5 | 181.0 ± 34.5 | 174.7 ± 29.5 | NS |
| Triglycerides (mg/dL) | 230.6 ± 147.1 | 106.6 ± 30.9 | 94.4 ± 30.0 | <0.01 |
| High density lipoprotein cholesterol (mg/dL) | 37.6 ± 7.7 | 36.2 ± 6.6 | 49.9 ± 9.4 | <0.01 |
| Low density lipoprotein cholesterol (mg/dL) | 116.4 ± 30.0 | 115.9 ± 35.6 | 109.2 ± 27.6 | NS |
| Uric acid (mg/dL) | 6.9 ± 1.8 | 5.5 ± 1.5 | 7.1 ± 3.0 | <0.05 |
| HOMA-IR index | 4.7 ± 3.8 | 1.2 ± 0.7 | 1.0 ± 0.5 | <0.001 |
| HOMA-β index | 116.9 ± 148.4 | 67.0 ± 41.3 | 74.4 ± 109.1 | NS |
| FLI | 87.1 ± 12.3 | 48.3 ± 25.0 | 29.6 ± 27.2 | <0.001 |
All data are reported as means ± standard deviations. BMI, body mass index; ABSI, a body shape index; HbA1c, glycated hemoglobin; ALT, alanine aminotransferase; AST, aspartate transaminase; Alk-p, alkaline phosphatase; γ-GT, gamma glutamyl transferase; HOMA-IR, homeostasis model assessment, insulin resistance; HOMA-β, homeostasis model assessment-β; FLI, fatty liver index. # p value in the groups (Friedman’s analysis of variance).