Figure 3.

Changes in the bacterial and fungal burdens and community diversity during the development of oral candidiasis. (A) Changes in Plaque Index between baseline and the first visit with candidiasis. (B) Changes in salivary bacterial load as subjects developed oral candidiasis and after antifungal treatment. (C) Changes in salivary Candida load in all subjects, during the chemotherapy cycle. (D–F) Changes in Candida load, bacteriome diversity, and mycobiome diversity, as subjects developed oral candidiasis and after antifungal treatment. *indicates a p value < 0.05, when comparing subject-matched data via Wilcoxon Rank tests.