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. 2019 Jun 25;16(12):2248. doi: 10.3390/ijerph16122248

Table 1.

Demographic features, underlying diseases, comorbidities, and clinical presentations of 412 patients with infective endocarditis.

Baseline Characteristics DM (72) Without DM (340) p
Age 55.9 ± 11.7 44.2 ± 17.1 0.001
Male 75% (54) 79.4% (270) 0.407
Comorbidity
CHD 6.9% (5) 15.3% (52) 0.06
CKD 26.4% (19) 8.8% (30) 0.001
HTN 51.4% (37) 23.3 (79) 0.001
LC 10.4% (5) 4% (10) 0.099
Malignancy 4.2% (3) 2.4% (8) 0.386
Rheumatic heart disease 11.1% (8) 17.9% (61) 0.159
Prosthetic valve 4.2% (3) 13% (44) 0.033
Previous endocarditis 11.1% (8) 5.9% (20) 0.109
ACCI score 3.24 2.13 0.002
IV drug user 8.3% (6) 28.5% (97) 0.001
Diabetic status
Oral DM 84.7% (61) 0% 0.001
Insulin DM 15.3% (11) 0% 0.001
Dyspnea 18% (13) 16.2% (55) 0.696
Neurological symptoms 16.7% (12) 13.5% (46) 0.687
Constitutional symptoms 18.1% (13) 7.6% (26) 0.006
Time from admission to the diagnosis of IE (hours) 89 (64–127) 56 (32–89) 0.032

CHD, congenital heart disease; CKD, chronic kidney disease; DM, diabetes mellitus; HTN, hypertension; IV, intravenous; IE, infective endocarditis; LC, liver cirrhosis.