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. 2019 Jun 8;8(6):822. doi: 10.3390/jcm8060822

Table 1.

The half-maximal inhibitory concentration (IC50) of gemcitabine, paclitaxel and combination gemcitabine with an IC75 dose of paclitaxel in vector control and Snail overexpressing Panc1 cells. Combination treatment was given under both high and no glucose media conditions.

Panc1 Gemcitabine Paclitaxel * Gemcitabine + IC 75 Paclitaxel
High Glucose No Glucose
Vector 1.8 (1.2–2.9) × 10−7 3.3 (2.4–4.6) × 10−9 1.3 (0.5–4.2) × 10−7 1.3 (0.3–5.3) × 10−7
Snail 1.4 (0.8–2.9) × 10−7 2.0 (1.3–3.1) × 10−9 3.0 (1.1–8.6) × 10−7 6.3 (0.4–52.2) × 10−7

IC50 (M) with 95% confidence interval. Vector compared with Snail overexpression: * p < 0.05.