Saliva and serum antibody levels according to endodontic findings. The patients were divided into groups according to the presence of root canal fillings, widened periapical spaces, and apical periodontitis. Saliva (A, B) and serum (C) IgA- and IgG-class antibodies were determined. The bacterial antigens included A. actinomycetemcomitans, P. gingivalis, P. intermedia, P. endodontalis, and T. forsythia. The antigens giving rise to cross-reactive antibodies included MAA-LDL, Rgp-44, and Aa-HSP60. White columns depict the absence of the endodontic finding and black columns depict the presence of the endodontic finding. Means and standard errors are shown. The asterisks depict statistical significance between the groups defined by the t-test after logarithmic transformation: * p < 0.05, ** p < 0.01. *** p < 0.001.