Table 4.
Genotype frequency of -589G/C GADD45a, -712C/T GADD45b in DR4-positive and DR4-negative RA patients.
| DR4 Positive | DR4 Negative | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| GADD45a Genotype | RA (n = 103) | Control (n = 20) | OR | p-Value | RA (n = 122) | Control (n = 89) | OR | p-Value | |
| n (%) | n (%) | 95% CI | n (%) | n (%) | 95% CI | ||||
| -589 G/C (rs581000) | GG + GC | 82 (79.61%) | 18 (90.00%) | 1 | NS | 113 (92.62%) | 73 (82.02%) | 1 | 0.029 |
| CC | 21 (20.39%) | 2 (10.00%) | 2.3 (0.5~10.72) | 9 (7.38%) | 16 (17.98%) | 0.36 (0.15~0.87) | |||
| DR4 Positive | DR4 Negative | ||||||||
| GADD45b Genotype | RA (n = 103) | Control (n = 20) | OR | p-Value | RA (n = 122) | Control (n = 89) | OR | p-Value | |
| n (%) | n (%) | 95% CI | n(%) | n (%) | 95% CI | ||||
| -712 C/T (rs3795024) | CC | 90 (87.37%) | 19 (95%) | 1 | NS | 112 (91.8%) | 73 (82.02%) | 1 | 0.033 |
| CT | 13 (12.63%) | 1 (5%) | 2.74 (0.34~1.21) | 10 (8.2%) | 16 (17.98%) | 0.41 (0.18~0.95) | |||
OR: odds ratio. CI: confidence interval.