Table 1.

The marked effects on human physiology of hypobaric hypoxia exposure over time is showed by the significative modification of blood capillary values SpO₂ (peripheral capillary oxygen saturation) and clinical parameters such as Heart Rate (HR) and Breath Rate (BR).

	BL (n = 15)	24 h (n = 14)	72 h (n = 14)	Repeated measures ANOVA P	P after Bonferroni correction
	Mean	Mean	Mean		24 h vs. BL	72 h vs. BL	24 h vs 72h
SpO2, %	98.93 ± 1.17	87.67 ± 3.48	91.71 ± 2.13	<0.001	<0.001	<0.001	0.001
HR, bpm	61.53 ± 7.99	83.07 ± 10.6	74.57 ± 13.69	<0.001	<0.001	0.01	0.24
BR*, rpm	13 ± 2.42	15.86 ± 3.01	15.44* ± 3.57	<0.001	0.01	0.02	0.87
LLS	0 ± 0	0.60 ± 0.74	0.36 ± 0.50	0.23	0.11	0.25	1

Only the BR seems to be less sensitive to hypoxia and its variations at specific time points are only marginally significant. Values are means ± SD. *BR was evaluated in 9 subjects.