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. 2019 May 30;9(6):296. doi: 10.3390/ani9060296

Table 1.

Genomic region and associated genes of the top 20 significant |iHS| 3.

BTA 1 Position (Mbp) NO. of SNP 2 (n) Mean |iHS| Value Candidate Genes Gene Name
2 30.1–30.2 22 2.198 SCN9A Bos taurus sodium voltage-gated channel alpha subunit 9
2 134.4–134.5 34 2.098 TAS1R2 Bos taurus taste 1 receptor member 2
3 14.8–14.9 38 2.502 ARHGEF2 Bos taurus Rho/Rac guanine nucleotide exchange factor (GEF) 2
3 14.8–14.9 38 2.502 KIAA0907 Bos taurus KH domain containing 4, pre-mRNA splicing factor
3 14.8–14.9 38 2.502 RXFP4 Bos taurus relaxin family peptide/INSL5 receptor 4
3 14.8–14.9 38 2.502 SSR2 Bos taurus signal sequence receptor subunit 2
3 7.2–7.3 40 2.298 NOS1AP Bos taurus nitric oxide synthase 1 adaptor protein
3 6.6–6.7 32 2.119 DDR2 Bos taurus discoidin domain receptor tyrosine kinase 2
3 6.6–6.7 32 2.119 HSD17B7 Bos taurus hydroxysteroid 17-beta dehydrogenase 7
5 69.2–69.3 16 2.332 C5H12orf75 Bos taurus chromosome 5 C12orf75 homolog
5 37.3–37.4 16 2.261 ADAMTS20 Bos taurus ADAM metallopeptidase with thrombospondin type 1 motif 20
5 29.1–29.2 19 2.126 METTL7A Bos taurus methyltransferase like 7A
5 28.3–28.4 38 1.982 SCN8A Bos taurus sodium voltage-gated channel alpha subunit 8
9 97.6–97.7 13 2.049 AIRN Bos taurus antisense IGF2R RNA noncoding
9 97.6–97.7 13 2.049 IGF2R Bos taurus insulin-like growth factor 2 receptor
10 11.5–11.6 42 2.415 TXNDC16 Bos taurus thioredoxin domain containing 16
10 11.4–11.5 28 2.05 ERO1A Bos taurus endoplasmic reticulum oxidoreductase 1 alpha
10 11.4–11.5 28 2.05 PSMC6 Bos taurus proteasome 26S subunit, ATPase 6
10 10.4–10.5 22 1.985 HOMER1 Bos taurus homer scaffold protein 1
11 81.1–81.2 14 2.374 VSNL1 Bos taurus visinin like 1
13 60.7–60.8 14 1.945 ANGPT4 Bos taurus angiopoietin 4
13 60.7–60.8 14 1.945 FAM110A Bos taurus family with sequence similarity 110 member A
17 63.5–63.6 39 2.169 SLC8B1 Bos taurus solute carrier family 8 member B1
22 49.2–49.3 13 1.958 ALAS1 Bos taurus 5′-aminolevulinate synthase 1
22 49.2–49.3 13 1.958 POC1A Bos taurus POC1 centriolar protein A
22 49.2–49.3 13 1.958 TLR9 Bos taurus toll like receptor 9
22 49.2–49.3 13 1.958 TWF2 Bos taurus twinfilin actin binding protein 2
22 49.2–49.3 13 1.958 WDR82 Bos taurus WD repeat domain 82
26 45.9–46 30 2.162 ADAM12 Bos taurus ADAM metallopeptidase domain 12
28 33.5–33.6 26 2.277 KCNMA1 Bos taurus potassium calcium-activated channel subfamily M alpha 1
28 3.7–3.8 17 2.126 ARV1 Bos taurus ARV1 homolog, fatty acid homeostasis modulator

1 BTA: Bos taurus autosome, 2 SNP: Single nucleotide polymorphism, 3 |iHS|: the absolute value of integrated Haplotype Score.