Table 7.

Results of multivariate analysis of factors independently predicting the probability of overall, minor medical, major medical, minor surgical, and major surgical complications.

Complication	Variable	Complications rate	Univariate p-value	Multivariate p-value	OR (95% CI)
Overall	DM	Non-diabetic pts: 68.2% Diabetic pts: 38.9%	0.023†	0.043**	0.304 (0.096–0.963)
Overall	DGA	Pts without complications: 480 min Pts with complications: 598 min	0.001*	0.002**	1.006 (1.002–1.009)
Minor medical	DGA	Pts without complications: 494 min Pts with complications: 629 min	0.001*	0.0004**	1.008 (1.004–1.013)
Major medical	Previous RT	No previous RT: 8.3% Previous RT: 25%	0.121‡	0.021**	9.253 (1.394–61.427)
Major medical	Smoking habit	Non-smokers: 5.9% Smokers: 18.2%	0.145‡	0.058**	6.146 (0.942–40.075)
Major medical	ASA category	ASA 1–3: 7.8% ASA 4: 42.9%	0.010‡	0.052**	25.574 (0.972–672.920)
Minor surgical	Nodal status	N0: 14.9% N+: 30.6%	0.086†	0.055**	2.997 (0.978–9.187)
Major surgical	Age	Pts without complications: 80.3 years Pts with complications: 78.3 years	0.047*	0.096**	0.877 (0.752–1.024)
Major surgical	Type of defect	Soft tissues only: 14.3% Soft tissues and bone: 32.1%	0.055†	0.071**	2.794 (0.916–8.525)

CI, Confidence interval; OR, Odds ratio.

^*Mann-Whitney test.

^**Logistic regression test.

^†Chi-square test.

^‡Fisher's exact test. Bold values are for statistical significant values.