Table 1.
Baseline characteristics of patients with alcohol-related cognitive impairment at admission (total Montreal Cognitive Assessment (MOCA) score < 26), and per recovery status after 6 weeks (total MOCA score ≥ or < 26).
| All | Sex | Recovery at Discharge | |||
|---|---|---|---|---|---|
| N = 395 | Male N = 286 |
Female N = 108 |
Yes N = 177 |
No N = 218 |
|
| Sex (female), n (%) (n = 394) | 108 (27.34%) | - | - | 44 (25%) | 64 (29.36%) |
| Age, mean (SD) (n = 395) | 50.10 (9.79) | 49.56 (9.78) | 51.56 (9.74) | 50.18 (9.58) | 50.03 (9.98) |
| Number of years of education, mean (SD) (n = 389) | 10.57 (2.44) | 10.55 (2.47) | 10.60 (2.39) | 10.71(2.35) | 10.45 (2.51) |
| Number of previous detoxifications, mean (SD) (n = 252) | 2.92 (2.71) | 2.93 (2.93) | 2.89 (2.13) | 2.83(2.79) | 3.00 (2.66) |
| Age at AUD onset, mean (SD) (n = 365) | 33.84(11.43) | 32.97 (11.92) | 36.18 (9.75) | 34.60(11.53) | 33.22(11.34) |
| Daily alcohol consumption (g), mean (SD) ( n = 329) | 211.45 (116.41) | 225.27 (120.28) | 171.10 (90.94) | 215.14 (123.91) | 208.58 (110.48) |
| Cannabis use disorder (yes), n (%) (n=395) | 66 (16.71%) | 46 (16.43%) | 18 (16.67%) | 30 (16.95%) | 36 (16.51%) |
| Tobacco use disorder (yes), n (%) (n=395) | 285 (72.15%) | 208 (72.72%) | 76 (70.37%) | 127 (71.75%) | 158 (72.48%) |
| BMI, mean (SD) (310) | 26.03 (5.43) | 25.91 (5.44) | 26.33 (5.44) | 26.26 (5.57) | 5.32 (25.86) |
| Metabolic disorders, n (%) (n=394) | 75 (18.99%) | 55 (19.29%) | 20 (18.51%) | 29 (16.38%) | 46 (22.02%) |
| Cirrhosis (yes), n (%) (n = 395) | 65 (16.46%) | 53 (18.53%) | 12 (11.11%) | 32 (18.08%) | 33 (15.14%) |
| MOCA score at admission | |||||
| Total score, mean (SD) * (n = 395) | 21.36 (3.04) | 21.34 (3.04) | 21.42 (3.05) | 22.25 (2.30) | 20.65 (3.36) |
| Visuospatial/executive (/5), mean (SD) * | 2.83 (1.30) | 2.88 (1.31) | 2.69 (1.29) | 2.10 (1.270) | 2.71 (1.32) |
| Naming (/3), mean (SD) | 2.90 (0.33) | 2.90 (0.34) | 2.90 (0.30) | 2.91 (0.31) | 2.89 (0.35) |
| Attention_1 (/2), mean (SD) | 1.34 (0.67) | 1.31 (0.68) | 1.43 (0.64) | 1.37 (0.65) | 1.32 (0.69) |
| Attention_2 (/1), mean (SD) | 0.87 (0.34) | 0.89 (0.32) | 0.81 (0.39) | 0.89 (0.32) | 0.36 (0.85) |
| Attention_3 (/3), mean (SD) * | 2.27 (0.93) | 2.36 (0.89) | 2.03 (0.98) | 2.45 (0.77) | 2.12 (1.02) |
| Language_1 (/2), mean (SD) * | 1.69 (0.53) | 1.69 (0.44) | 1.69 (0.57) | 1.76 (0.48) | 1.63 (0.57) |
| Language_2 (/1), mean (SD) | 0.29 (0.45) | 0.27 (0.44) | 0.33 (0.47) | 0.32 (0.47) | 0.26 (0.44) |
| Abstraction (/2), mean (SD) | 0.78 (0.68) | 0.76 (0.69) | 0.83 (0.68) | 0.80 (0.70) | 0.77 (0.67) |
| Delayed recall (/5), mean (SD) * | 2.91 (1.36) | 2.82 (1.41) | 3.16 (1.19) | 3.15 (1.29) | 2.72 (1.39) |
| Orientation (/6), mean (SD) * | 5.49 (0.72) | 5.47 (0.71) | 5.55 (0.74) | 5.64 (0.58) | 5.37 (0.80) |
*: significant between groups with recovery status differences (Mann Whitney test).