Table 5.
Commonly used generic and disease-specific quality of life instruments in CLI studies
| QOL instrument | Abbreviation | Domains | Scoring |
|---|---|---|---|
| Short-Form 36 or RAND Short-Form 36 | SF-36 or RAND-36 | 36 items assessing 8 health-related concepts including physical functioning, bodily pain, general health, vitality, social functioning, mental health, and emotional well-being. The measure also yields psychometrically-based physical and mental health summary scores. | 0 to 100 |
| Short-Form 6 Dimension | SF-6D | The SF-6D health index is designed for calculating Quality Adjusted Life Years (QALYs), which are used to estimate the cost-effectiveness of health interventions. | 0 to 1 |
| EuroQol-5D (Utility Measure) EuroQol-Visual Analog Scale |
EQ-5D EQ-VAS |
A descriptive system of 5 dimensions including mobility, self-care, usual activities, pain/discomfort, and anxiety/depression. Visual analog scale from 0 to 100. |
EQ-5D Items: 0–1 VAS: 0–100 |
| Nottingham Health Profile | NHP | 38 statements addressing 6 health-related concepts including energy, pain, emotional reaction, sleep, social isolation, and physical mobility. | 0–100 |
| FLeQKI [German] | FLeQKI [German] | 35 items addressing 7 domains including comorbidity, physical pain, physical functioning, physical state, social functioning, mental health, and therapy-induced limitations. | |
| Vascular Quality of Life Questionnaire | VascuQOL-25 VascuQOL-6 |
25 questions assessing 5 domains including pain, symptoms, activities, social well-being, and emotional well-being. 6 items assessing the same 5 domains listed above. |
1–7 6–24 |
| Walking Impairment Questionnaire | WIQ | 16 questions assessing 4 domains including symptoms, distance, speed, and climbing. | 0–100 |
| World Health Organization Quality of Life Assessment Instrument | WHOQOL-100 WHOQOL-BREF |
100 questions assessing physical health, psychological health, social relationships, and environment. 26 questions assessing 4 domains including physical health, psychological health, social relationships, and environment. |
0–100 0–100 |