. 2019 Jul 1;15:187–208. doi: 10.2147/VHRM.S209241

Table 8.

Index CLI hospitalization costs

Publication	Country/region	Data source (years)	Currency	Population details	Methods	Total cost
Reinecke (2015)²⁶	Germany	German health insurer data (2009–2011)	Euro	Hospitalized CLI patients	ICD-10 dx and German procedure (OPS) codes to identify cases and procedures	Mean Cost 2011: €5,316 (Rutherford 4) 2011: €6,021 (Rutherford 5) 2011: €8,461 (Rutherford 6)
Agarwal (2016)²²	United States	Nationwide Inpatient Sample (2003–2011)	2015 USD	Hospitalized CLI patients	ICD-9 diagnosis and procedure codes used to identify cases and procedures	Mean Cost 2003: ~$23,000 2007: ~$23,000 2011: ~$23,000
Dua (2016)⁶³	United States	Nationwide Inpatient Sample (2001–2011)	2015 USD	Elective admissions to treat CLI	ICD-9 diagnosis and procedure codes used to identify cases and procedures	Median Cost 2001: $12,568 2004: $15,588 2007: $17,964 2011: $20,587
Freisinger (2017)³²	Germany	German health insurer data (2009–2011)	Euro	Hospitalized CLI patients with tissue loss	ICD-10 dx and German procedure (OPS) codes to identify cases and procedures	Mean Cost Rutherford 5 2011: €5,975 (with DM) 2011: €6,058 (without DM) Rutherford 6 2011: €8,860 (with DM) 2011: €8,080 (without DM)
Martinez (2018)⁶⁴	United States	Nationwide Readmissions Database (2013–2014)	USD	CLI patients undergoing revascularization procedures	ICD-9 diagnosis and procedure codes used to identify cases and procedures	Mean Cost Index admission: $29,148 Readmission: $17,681

Abbreviations: CLI, critical limb ischemia; DM, diabetes mellitus; ICD-9/10, International Classification of Diseases 9th/10th Revision; OPS, Operationen und Prozedurenschlüssel [German procedure classification]; USD, US dollar.