Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Jul 10;19:677. doi: 10.1186/s12885-019-5867-y

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

PMC Copyright notice

Fig. 3 — APC2-deficiency impairs follicular growth in the ovary. a Histogram showing total number of primary (1ry), secondary (2ry), antral and pre-ovulatory follicles in Apc2^+/+ and Apc2^−/− ovarian sections (mean ± SE; n = 4; no significant differences, t-test). b Size distribution of healthy antral and pre-ovulatory follicles (mean ± SE; n = 4; *P < 0.05, t-test). c Histogram showing a > 2-fold increase of apoptosis in granulosa cells of Apc2^−/− follicles (mean ± SE; n = 4; *P < 0.05, t-test). d, e Representative photomicrographs of cleaved caspase 3 immunostaining in (d) Apc2^−/− and (e) Apc2^+/+ granulosa cells. Bars = 100 μm