Table 2.
Characteristics of patients at microbial diagnosis
| MRSA respiratory ICU infection (n = 25) | Linezolid (15) | Vancomycin (10) | p value |
|---|---|---|---|
| Respiratory infection | 0.76 | ||
| Tracheobronchitis | 2 | 2 | |
| HAP | 2 | 2 | |
| VAP | 8 | 5 | |
| Early onset VAP | 4 | 4 | |
| Late onset VAP | 4 | 1 | |
| Severe CAP | 3 | 1 | |
| Type of sample | 0.24 | ||
| BAL | 2 | 0 | |
| BAS | 10 | 10 | |
| ETA | 2 | 0 | |
| Pleural fluid | 1 | 0 | |
| Microbial diagnostic | |||
| Log CFU/mL | 6.0[4.0–6.0] | 5.0[4.0–6.0] | 0.40 |
| Polymicrobial respiratory infection | 7 | 3 | 0.69 |
| Radiographic consolidation | 0.34 | ||
| None | 2 | 0 | |
| Monolateral | 2 | 3 | |
| Bilateral | 11 | 7 | |
| Severity scores | |||
| APACHE II ICU at microbial diagnosis | 17.0[11.5–22.8] | 17.5[6.5–22.3] | 0.58 |
| SOFA ICU at microbial diagnosis | 8.0[1.8–10.0] | 7.0[5.5–10.8] | 0.55 |
Data are presented as median and interquartile range [percentiles 25th–75th] or n (%). ICU intensive care unit, HAP hospital-acquired pneumonia, VAP ventilator-associated pneumonia, CAP community-acquired pneumonia, BAL bronchoalveolar lavage, BAS tracheobronchial aspirates, ETA endotracheal aspirates, APACHE II Acute Physiology and Chronic Health Evaluation, SOFA Sequential Organ Failure Assessment, MRSA methicillin-resistant S. aureus, CFU colony-forming units