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. 2019 Jul 9;11:100. doi: 10.1186/s13148-019-0695-0

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© The Author(s). 2019

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 7 — Gastric in silico set unsupervised hierarchical clustering analysis based on the average methylation β value for each of the aberrantly methylated CGI. Heatmap obtained by UHC of 248 gastric cancer samples. Two groups of GC branched separately according to their methylation levels. A subgroup with high methylation values in all CGIs is enclosed in a dashed box. To the right of the heatmap, subtype information are reported: MSI microsatellite instability, CIN chromosomal instability, GS genomic stability, EBV Epstein-Barr virus positivity