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. 2019 Jul 9;11:100. doi: 10.1186/s13148-019-0695-0

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© The Author(s). 2019

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 8 — Methylation values obtained from the biliary tract cancer discovery dataset and the in silico dataset. a Genomic organization of PCDHG@, including the localization of exons, CGIs (annotated with the UCSC CGI name) and CTCF binding sites. b Mean β values, resulting from the average of the samples (normal and tumour) of each probe of the altered CGIs obtained using EPIC array. c Mean methylation values of each probe, belonging to the CpG 45 and CpG 41, obtained from the in silico datasets TCGA-CHOL (450K array). Tumour: Gbc, gallbladder cancer; Extra chol, extrahepatic cholangiocarcinoma; Intra chol, intrahepatic cholangiocarcinoma. Normal: Gb, gallbladder; Extra, extrahepatic; Intra, intrahepatic