Table 3.
Altered CGIs in gastric cancer
| UCSC CGI | UCSC CGI name | CTCF binding site | Δβ value (GC-control) |
Genes within region | Gene promoter-associated CGI |
|---|---|---|---|---|---|
| chr5:140762401-140762768 | CpG 28 | chr5:140761029-140763470 | 0.241 | PCDHGA1, PCDHGA2, PCDHGA3, PCDHGA4, PCDHGA5, PCDHGA6, PCDHGA7, PCDHGB1, PCDHGB2, PCDHGB3 | PCDHGA7 |
| chr5:140787447-140788044 | CpG 45 | chr5:140786247-140788714 | 0.210 | PCDHGA1, PCDHGA2, PCDHGA3, PCDHGA4, PCDHGA5, PCDHGA6, PCDHGA7, PCDHGA8, PCDHGA9, PCDHGB1, PCDHGB2, PCDHGB3, PCDHGB4, PCDHGB5, PCDHGB6 | PCDHGB6 |
| chr5:140855386-140856620 | CpG 95 | chr5:140854218-140856648 | 0.212 | PCDHGA1, PCDHGA10, PCDHGA11, PCDHGA12, PCDHGA2, PCDHGA3, PCDHGA4, PCDHGA5, PCDHGA6, PCDHGA7, PCDHGA8, PCDHGA9, PCDHGB1, PCDHGB2, PCDHGB3, PCDHGB4, PCDHGB5, PCDHGB6, PCDHGB7, PCDHGC3 | PCDHGC3 |
| chr5:140864527-140864748 | CpG 22 | – | 0.243 | PCDHGA1, PCDHGA10, PCDHGA11, PCDHGA12, PCDHGA2, PCDHGA3, PCDHGA4, PCDHGA5, PCDHGA6, PCDHGA7, PCDHGA8, PCDHGA9, PCDHGB1, PCDHGB2, PCDHGB3, PCDHGB4, PCDHGB5, PCDHGB6, PCDHGB7, PCDHGC3, PCDHGC4 | PCDHGC4 |
Note: CGI CpG island, GC gastric cancer. CpG 28, 45, 95 and 22 correspond to UCSC CGI name