Table 2.
Univariate Cox proportional hazards analysis of BCR-free survival in TCGA cohort including PC patients treated by radical prostatectomy
| Variable | P value | Hazard ratio [95% CI] |
|---|---|---|
| Age (> 60 vs. ≤ 60) | 0.8385 | 0.944 [0.545, 1.637] |
| pT3-4 vs. pT2 | < 0.001 | 7.266 [2.617, 20.172] |
| pN1 vs. pN0 | 0.025 | 2.045 [1.094, 3.823] |
| Gleason score | < 0.001 | 4.244 [2.256, 7.981] |
| Preoperative PSA | 0.0015 | 1.025 [1.009, 1.04] |
| R1 vs. R0 | 0.0231 | 1.902 [1.092, 3.312] |
| SLCO4C1 methylation | ||
| cg06480736 (continuous) | < 0.001 | 15.914 [3.863, 65.565] |
| cg19774478 (continuous) | < 0.001 | 9.001 [2.789, 29.054] |
| cg19788741 (continuous) | 0.003 | 10.759 [2.203, 52.553] |
| cg22149516 (continuous) | 0.006 | 17.144 [2.295, 128.066] |