Table 2.
Details of the 10 centric proteins in the PPI network
| Protein name | UniProt Accession No. | Symbol | MW [kDa] | Calc. pI | Fold Change* | Regulation* | Functional classification |
|---|---|---|---|---|---|---|---|
| Serum albumin | P07724 | ALB | 69.6 | 6.38 | 0.382 | Down | complement and coagulation cascades |
| Cytochrome c | P62897 | CYCS | 11.7 | 9.50 | 2.1140 | UP | the actin cytoskeleton |
| ATP synthase subunit d | Q9DCX2 | ATP5H | 18.4 | 5.27 | 3.1530 | UP | oxidative phosphorylation |
| Gelsolin | P13020 | GSN | 84.7 | 6.32 | 0.4911 | Down | the actin cytoskeleton |
| NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 | Q9CQ75 | NDUFA2 | 11.1 | 9.91 | 2.0884 | UP | oxidative phosphorylation |
| Actin-like protein 7B | Q9QY83 | ACTL7B | 45.5 | 5.59 | 2.2407 | UP | the actin cytoskeleton |
| Actin-related protein T2 | Q9D9L5 | ACTRT2 | 41.7 | 5.85 | 2.0865 | UP | the actin cytoskeleton |
| Myosin-9 | Q8VDD5 | MYH9 | 224.9 | 5.77 | 0.3635 | Down | the actin cytoskeleton |
| Cytochrome c oxidase subunit 6C | Q9CPQ1 | COX6C | 8.6 | 10.14 | 2.0688 | UP | oxidative phosphorylation |
| Fibronectin | P11276 | FN1 | 272.1 | 5.63 | 0.3553 | Down | complement and coagulation cascades |