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Lamotrigine plasma concentrations and corresponding life charts. Lamotrigine plasma concentrations are in milligram/liter and intervals in hours after last lamotrigine dosage. *Average difference: difference between the average of the two concentrations during COC use and the concentration on day 6 or 7 without COC. **Day 6 (patient 1) and day 7 (patient 2) of the pill‐free week [Colour figure can be viewed at wileyonlinelibrary.com]
