Table 5.
Study | Low vision | Blindness | Skin disease/troublesome itch | Source |
---|---|---|---|---|
Assumed productivity loss | ||||
Benton & Skinner 67 | ‐ | 100% | ‐ | |
Kim & Benton 58 | ‐ | 100% | ‐ | |
McFarland & Murray 124 | Not available | Not available | Not available | |
Benton 125 | ‐ | Unclear | ‐ | |
Haddix 69 | ‐ | Not available | ‐ | |
Kim et al. 60 | Patient: 38% Caregiver: 5% | Patient: 79% Caregiver: 10% | Severe itching: 19% | 128, 129, 134, 135, 136, 137 |
Redekop et al. 59 | 38% | 79% | Moderate: 10% Mild: 0% | 128, 129 |
Healthy life year weightsa | ||||
Prescott et al. 126, 127 | ‐ | 1.0 | ‐ | |
Evans et al. 71 | ‐ | 0.5 | ‐ | |
Benton 125 | ‐ | 1.0 | ‐ | |
DALY weightsa | ||||
GBD 1990 | 0.245 | 0.488 (treated) 0.600 (untreated) | 0.068 | GBD 1990 138 |
GBD 2000 138 | 0.224 (treated) 0.282 (untreated) | 0.60 | 0.068 | GBD 2000 138 |
McFarland & Murray 124 | Not available | Not available | Not available | |
Turner et al. 73 | 0.170 | 0.594 | 0.068 | GBD 2004 139 |
Coffeng et al. 30 | 0.282 | 0.594 | 0.068 | GBD 2004 139 |
Coffeng et al. 78 | 0.033 | 0.195 | 0.108b | GBD 2010 140 |
de Vlas et al. 141 | 0.101c | 0.101c | 0.079b | GBD 2010 140 |
DALYs, disability‐adjusted life years; GBD, Global Burden of Disease Study.
Reflect the severity of the disease sequelae with 0 representing perfect health and 1 representing death.
Used a weight representing an overall average for skin disease across more finely disaggregated strata/severity levels.
Used a weight representing an overall average for visual morbidity (i.e. the weight was not stratified by ‘low vision’ and ‘blindness’).
Where relevant additional studies that were not performing economic evaluations were included for comparison.