Figure 2.

Baseline expression levels of BCL2 family members and sensitivity to BH3 mimetics in prostate cancer cell lines. A, BCL2 family protein expression. GAPDH was used as a loading control. B, BCL2 family gene expression. mRNA transcript levels were normalized to GAPDH. C‐E, Viability was measured in cells exposed to increasing concentrations of ABT‐199 (C), ABT‐263 (D), or A‐1210477 (E) for 72 hours and shown as percent of vehicle‐treated control. Values represent the mean ± SEM from three independent experiments. GAPDH, glyceraldehyde 3‐phosphate dehydrogenase; mRNA, messenger RNA