Table 1.
Adapted from Smack et al. [3]
| Classification | Main demographic | Familial patterns | Common Sites | Serum Electrolyte Level | Clinical Presentation |
|---|---|---|---|---|---|
| Primary Normophosphatemic TC |
- Onset before 2nd decade (63%) - Mostly involve patients in tropical or subtropical regions - No sexual predilection |
- Nil familial pattern |
- Hip (31%) - Elbow (24%) - Knee (16%) |
- Normal serum phosphate - Normal serum calcium |
- Solitary calcification predominates (66%) - History of trauma - Milky fluid of calcification on incision are common |
| Primary Hyperphosphatemic TC |
- Onset before 2nd decade (82%) - No sexual predilection - Higher frequency in blacks and men |
- Strong familial pattern - Most patients are siblings (74%) |
- Hip (37%) - Elbow (27%) - Shoulder (23%) |
- Elevated serum phosphate - Elevated serum calcium |
- Multiple calcifications predominate (74%) - Milky fluid of calcification on incision in all cases reviewed |
| Secondary TC |
- Onset before 2nd decade (51%) - Higher frequency in whites and women - Chronic renal failure is the most common identifiable condition |
- Some familial pattern |
- Hip (29%) - Elbow (24%) - Shoulder (17%) |
- Elevated serum calcium |
- Multiple calcifications predominate (80%) - Milky fluid of calcification on incision in all cases reviewed |