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. 2019 Jul 10;17:82. doi: 10.1186/s12951-019-0514-y

Table 2.

Most commonly used antimicrobial agents in wound treatment

Antimicrobial agents Administration Spectrum References
Gentamicin Systemic/topical Gram-positive bacteria [98]
Tetracycline Oral/topical Gram-positive and Gram-negative bacteria [99, 100]
Ciprofloxacin Oral/systemic Gram-positive and Gram-negative bacteria especially Gram-negative bacilli [101, 102]
Vancomycin Systemic Gram-positive bacteria especially MRSA [103]
Penicillin G Systemic Non-β-lactamase-producing Gram-positive bacteria, anaerobes [104]
Neomycin Systemic/topical Aerobic Gram-negative bacilli and Gram-positive aerobes [105]
Polymyxin B Systemic Gram-negative bacteria [106]
Mupirocin Topical Gram-positive bacteria especially MRSA, some Gram-negative flora [107]
Amphotericin B Systemic/topical Fungi [108]
Silver sulfadiazine Topical Gram-positive, most Gram-negative bacteria, and some fungal forms [109]
Mafenide acetate Topical Gram-negative bacilli, anaerobes [110]