Fig. 2.

Neuroradiological examination by magnetic resonance imaging (MRI): (a) mid-sagittal MRI (T1 weighted image, T1WI) of the brain of patient II-5 (male proband; 49 years old at the time of MRI, 21 years after disease onset; and (b) mid-sagittal MRI (T1WI) of the brain of II-7, male sibling of proband; 48 years old at the time of MRI, 22 years after disease onset). The arrows indicate cerebellar atrophy