Fig. 4.
NKG2D-BBz CAR-T cells showed effective and persistent antitumor activity against xenografts formed by U-251MG cells in mice. a B-NDG mice were injected with 1 × 106 stable luciferase transfected U-251MG cells subcutaneously and imaged 7 days prior to T cell infusion. After mice received T cells treatment, photographs were taken serially at indicated time. b Comparison of tumor bioluminescent signal among the indicated groups at different time points