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. 2019 Jan 28;105(6):1099–1110. doi: 10.1002/JLB.4HI0918-364RR

Figure 3.

Figure 3

Topical application of anti‐psl MAb Cam003 is not protective. (A) Percent OPK of P. aeruginosa 6294 grown in a planktonic and microaggregate form. The anti‐Psl mAb Cam003 shows significant opsonophagocytic killing against 6294, which is decreased when bacteria are allowed to form microaggregates in vitro. Student's t test. (B) Topical application of 400 μg of Cam 003 onto infected eyes does not improve bacterial clearance. The mAb‐treated eyes show a 2‐fold increase in bacterial presence. Student's t test. P = 0.01. Data are representative of three independent experiments. (C) No significant differences in tissue IL‐1β, MIP‐2, and NE levels among Cam 003‐treated and control Ab‐treated mice. Student's t test. Each symbol represents individual animals