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. 2019 Apr 29;70(1):294–307. doi: 10.1002/hep.30604

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© 2019 The Authors. Hepatology published by Wiley Periodicals, Inc., on behalf of American Association for the Study of Liver Diseases.

This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.

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Conditional analysis of genotyped and imputed HLA SNPs, AAs, and classical alleles with anti‐sp100 subphenotype in the PBC GWA cohort. (A) Association results before conditional analysis, marked with AA77 in HLA‐DRβ1. (B) Conditional analyses controlling for HLA‐DRβ1 AA77 and AA37. (C) Conditional analysis by further controlling for HLA‐DPβ1 AA65. (D) Association results before conditional analysis, marked with DRB1*0301 in the DRB1 locus. (E) Conditional analysis by controlling for DRB1*0301, DRB1*1501, and DRB1*01. (F) Conditional analysis by further controlling for DPB1*0301.