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. 2019 May 20;24(4):e12598. doi: 10.1111/hel.12598

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© 2019 The Authors. Helicobacter Published by John Wiley & Sons Ltd.

This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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Localization of Helicobacter pylori cells in mucous layer attached to gastric foveolar epithelial cells. Serial histologic sections of a sample with prominent H. pylori infection were used for hematoxylin & eosin staining (A) and IHC with TMDU‐mAb (B) followed by immuno‐electron microscopy (C). (A and B) show an identical area of the H. pylori‐infected gastric mucosa. The area with immunoreactive H. pylori indicated by an arrow in b was subjected to immuno‐electron microscopy. (c) Several H. pylori organisms with a dense rim‐staining pattern indicated by arrows were observed on the foveolar epithelial cell. Bars: 20 µm (A and B), 1.0 µm (C)