Figure 6.

Proliferating parietal cells in gastric mucosa with Helicobacter pylori infection. Double‐enzyme IHC with anti‐proton pump antibody (blue) and anti‐Ki67 antibody (brown) was performed on samples with non‐atrophic superficial gastritis (A and B) or chronic atrophic gastritis (C and D): Non‐atrophic superficial gastritis samples exhibited many cells with nuclear signals of Ki67 in the neck zone (A and B). In chronic atrophic gastritis samples, many proton pump‐ and Ki 67‐positive cells were identified in a deeper area (C and D). Proton pump‐positive parietal cells showing nuclear Ki67 staining are indicated by arrows in (B and D). Bars: 50 µm