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. 2019 Apr 29;125(14):2445–2454. doi: 10.1002/cncr.32084

Table 4.

Mean Baseline Biomarker Values for Patients Enrolled in Part 2 (Intent‐To‐Treat Population)

Biomarker Ontuxizumab at 8 mg/kg + G/D (n = 139) Placebo + G/D (n = 70)
Endosialin lymphatic endothelial cell M score 12.8 13.3
Endosialin membranous tumor cell M score 4.2 4.3
Endosialin nonvascular stromal cell M score 18.3 18.7
Endosialin perivascular cell M score 24.1 22.9
Endosialin venous endothelial cell M score 19.1 16.8
Log plasma endosialin, ng/mL 11.463 11.486
PDGFR‐β arterial endothelial cell M score 3.4 3.2
PDGFR‐β capillary endothelial cell M score 30.0 29.0
PDGFR‐β cytoplasmic tumor cell M score 22.7 21.5
PDGFR‐β lymphatic endothelial cell M score 22.0 21.7
PDGFR‐β membranous tumor cell M score 8.3 4.7
PDGFR‐β nonvascular stromal cell M score 21.4 23.4
PDGFR‐β perivascular cell M score 31.8 29.8
PDGFR‐β venous endothelial cell M score 3.6 3.5
Log plasma PDGFR‐β, ng/mL 7.830 7.872

Abbreviations: G/D, gemcitabine and docetaxel; PDGFR‐β, platelet‐derived growth factor receptor β.