Table 5.

Adverse Events Experienced by All Subjects per Treatment Group, by MedDRA Preferred Term: Safety Analysis Set

	Mild Hepatic Impairment (N = 8)		Moderate Hepatic Impairment (N = 8)		Severe Hepatic Impairment (N = 6)		Normal Hepatic Function (N = 8)
SOC MedDRA PT	e	n (%)	e	n (%)	e	n (%)	e	n (%)
Total	4	1 (12.5)	1	1 (12.5)	0	0	0	0
Gastrointestinal disorders	3	1 (12.5)	0	0	0	0	0	0
Diarrhea	3	1 (12.5)	0	0	0	0	0	0
Investigations	0	0	1	1 (12.5)	0	0	0	0
Platelet count low	0	0	1	1 (12.5)	0	0	0	0
Nervous system disorders	1	1 (12.5)	0	0	0	0	0	0
Dizziness	1	1 (12.5)	0	0	0	0	0	0

e, number of times the adverse event occurred; MedDRA PT, Medical Dictionary for Regulatory Activities preferred term; N, number of subjects exposed; n, number of subjects that experienced the AE; SOC, system organ class.