Figure 5.

LABs modulate expressions of antiviral proteins and receptors in HCT116 cells. After HCT116 cells stimulated with LABs and PolyI:C for 3 and 12 h, the mRNA level of CXCL-10, OAS1, MxA, RIG-I, and TLR3 was evaluated by RT-PCR. Cells treated with either PolyI:C or medium alone were used as positive and negative controls, respectively. The positive control was used for comparison of LAB strains treated groups. The mean differences among the different superscript letters (a, b, ab, c, bc) were significant at 0.05 level. LABs stimulation decreased the level of CXCL-10, while increased level of other anti-viral proteins at 12 h in HCT116 cells, post-treated with PolyI:C.