Table 3:
(Phylum) OUT | Sequence | Prevalence | Abundance | Beta | p-value | FDR p-value |
---|---|---|---|---|---|---|
(F) Erysipelotrichaceae CC-115 | 807548 | 35.9% | 0.00018 | −0.37 | 0.00 | 0.04 |
(F) Megasphaera | 4410265 | 22.3% | 0.00034 | −0.34 | 0.02 | 0.11 |
(F) Coprobacillus | 415427 | 57.4% | 0.00014 | −0.29 | 0.00 | 0.04 |
(A) Adlercreutzia | 631764 | 63.3% | 0.00016 | −0.25 | 0.00 | 0.05 |
(F) Anaerotruncus | 315223 | 88.5% | 0.00050 | −0.25 | 0.01 | 0.09 |
(A) Eggerthella | 682726 | 47.7% | 0.00012 | −0.24 | 0.01 | 0.07 |
(B) Alistipes | 107044 | 65.4% | 0.00066 | −0.24 | 0.04 | 0.21 |
(F) Clostridia SHA-98 | 836693 | 55.5% | 0.00011 | −0.20 | 0.01 | 0.07 |
(F) Lachnospiraceae | 975306 | 100.0% | 0.05142 | 0.12 | 0.03 | 0.21 |
(F) Clostridium | 558420 | 99.5% | 0.00619 | 0.24 | 0.05 | 0.23 |
(C) Streptophyta | 262379 | 44.5% | 0.00017 | 0.24 | 0.01 | 0.07 |
(F) Lachnospira | 843553 | 99.7% | 0.01246 | 0.25 | 0.04 | 0.21 |
(B) Paraprevotellaceae | 157377 | 12.3% | 0.00028 | 0.28 | 0.04 | 0.21 |
(F) Peptococcaceae | 110317 | 49.3% | 0.00024 | 0.28 | 0.01 | 0.11 |
(F) Faecalibacterium | 368219 | 100.0% | 0.08248 | 0.35 | 0.01 | 0.09 |
(Fus) Cetobacterium | 828162 | 12.1% | 0.00101 | 0.45 | 0.00 | 0.00 |
(B) Prevotella | 568118 | 100.0% | 0.03760 | 0.50 | 0.02 | 0.11 |
all coefficients expressed per SD increase step count=3002 steps.
Table sorted by beta coefficient, with negative value and positive values indicating direction of association (zero = no association). Names are given by initial of phylum [(A) Actinobacteria, (B) Bacteroidetes, (C) Cyanobacteria, (F) Firmicutes, (Fus) Fusobacteria] and lowest taxonomy down to genus. Multivariate models adjusted for age, race, BMI, clinical center, library size, and # of chronic conditions (fall history, hip fracture, myocardial infarction, stroke, congestive heart failure, diabetes, cancer, COPD, rheumatoid arthritis, osteoarthritis, depression, visual impairment, Parkinson’s disease, and Alzheimer’s disease).