Figure 2.

Diminished SATB1 expression in human spleen. Representative FACS plots and summarized CD4⁺, CD8⁺ CD3⁺ T cell and CD19⁺ B cell populations in adult PBMCs (n = 6) (a) and their respective SATB1 expression as MFI‐fold change over B cells in PBMCs (b) spleen (n = 5) (d) and lymph node (n = 4) (f). CD27⁺ CD45RA ⁺, CD27⁺ CD45RA ⁻, CD27⁻ CD45RA ⁺, CD27⁻ CD45RA ⁻ T‐cell compartments of CD4⁺ and CD8⁺ T cells from adult PBMCs (c) with their respective SATB1 expression as representative histograms and MFI‐fold change over CD19⁺ B cells in PBMCs (c), spleen (e) and lymph node (g). One‐way ANOVA was performed between groups (*P ≤ 0.05; **P ≤ 0.01, ***P ≤ 0.001, ****P ≤ 0.0001). Experiments were performed once for each donor within each tissue.