Table 1.
List of selected differentially regulated genes (p53 null versus wildtype)
| Functional class | Fold change | Up/down |
|---|---|---|
| Oxidative stress | ||
| Sesn2 | 3.1 | Down |
| Dcxr | 24.7 | Down |
| Ephx1 | 2.1 | Down |
| Gpx7 | 2.3 | Up |
| Cox6b2 | 2.2 | Down |
| Wwox | 2 | Up |
| Cyp4f15 | 2.8 | Down |
| Ddit4l | 5.2 | Down |
| Neurogenesis | ||
| Otx1 | 3.4 | Up |
| Dcx | 2.8 | Up |
| Neurog2 | 4.3 | Up |
| Thy1 | 4.2 | Up |
| Nrxn3 | 3.4 | Up |
| Nr2f2 | 2.5 | Up |
| Bhlhe22 (negative regulation) | 4.5 | Down |
| Neurite extension/migration | ||
| Elav14 | 2.8 | Up |
| Prg3 | 2.4 | Up |
| Tagln3 | 3.1 | Up |
| Gdap111 | 2.1 | Up |
| Gdap1 | 2.2 | Up |
| Chl1 | 2.1 | Up |
| GABAergic | ||
| Gad1 | 2.4 | Up |
| Gabra3 | 2.2 | Up |
| Chl1 | 2.1 | Up |
| Glutamatergic | ||
| Grik2 | 2.4 | Up |
| Grin3a | 2 | Up |
| Grin2c | 3 | Up |
| Gria3 | 4.4 | Down |
| Camk2a | 2.5 | Up |
| Cholinergic | ||
| Chrnb1 | 2.7 | Up |
| Dopaminergic | ||
| Moxd1 | 2.2 | Up |
| K+ channels | ||
| Kcnj12 | 2.7 | Down |
| Kcnc1 | 4.8 | Down |
| Kctd4 | 4.7 | Up |
| Dpp10 | 2 | Up |
| Ca2+ channels | ||
| Cacng5 | 4.7 | Down |