Table 1.
Vaccines used and their antigen components.
| Abbreviation | Vaccine | Pertussis antigen content (μg) | TLR agonist (μg) | ||||
|---|---|---|---|---|---|---|---|
| PT* | PRN | FHA | FIM2,3 | TLR4A | TLR9A | ||
| DTwP | D.T.COQ/D.T.P | n.d. | n.d. | n.d. | n.d. | ||
| DTaP | DAPTACEL | 10 | 3 | 5 | 5 | ||
| Tdap | ADACEL | 2.5 | 3 | 5 | 5 | ||
| mTdap | N/A | 10 | 5 | 5 | 7.5 | ||
| mTdap/TLR4 | N/A | 10 | 5 | 5 | 7.5 | 5 | |
| mTdap/TLR9 | N/A | 10 | 5 | 5 | 7.5 | 250 | |
Chemically-detoxified PT in DTwP and DTaP; genetically-detoxified PT in mTdap, mTdap/TLR4, and mTdap/TLR9.
DTaP, diphtheria, tetanus, and acellular pertussis.
Tdap, reduced DTap.
mTdap, modified Tdap.