Table 3.
Biophysical properties of erg currentsa
| erg current | τ (ms), recovery from inactivation at −100 mV | τ (ms), deactivation at −100 mV | n | Activation curve V0.5 (mV) | k (mV) | n | % of maximum erg current activation during ramp pulse | n |
|---|---|---|---|---|---|---|---|---|
| r-erg1a | 4.3 ± 0.9 | 79.5 ± 30.9 | 3 | −41.9 ± 3 | 5.2 ± 0.5 | 3 | 3.0 ± 1.0 | 8 |
| r-erg1b | 3.3 ± 0.9 | 14.6 ± 1.5 | 5 | −25.4 ± 1.7 | 7.7 ± 0.9 | 6 | 3.7 ± 0.8 | 9 |
| r-erg2 | 5.9 ± 0.3 | 53.3 ± 4.0 | 4 | −2.0 ± 2.0 | 5.9 ± 0.7 | 6 | 1.8 ± 0.5 | 5 |
| r-erg3 | 2.1 ± 0.5 | 16.9 ± 1.9 | 4 | −44.2 ± 1.8 | 4.2 ± 0.6 | 7 | 15.0 ± 4.0 | 9 |
| erg Purkinje cells | 3.0 ± 0.5 | 22.8 ± 3.2 | 6 | −44.3 ± 0.4 | 4.9 ± 0.6 | 7 | ∼17 | 7 |
aBiophysical properties of heterologously expressed erg currents and native erg currents measured in Purkinje cells of neonatal mice (P5–P10). All measurements were performed in an extracellular solution containing 40 mm K+.