Stereotypical short-term changes following axonal lesion. A, Reconstruction of an axon targeted for lesion. The boxed area in red is shown in B. B, In vivo imaging of the axon in A showing short-term changes after axotomy including blebbing close to the lesion site (arrow), thinning of axon shaft, retraction of the cut axonal stump from the lesion site and eventual swelling of the axonal stump. p, Proximal; d, distal. Scale bar, 5 μm.