Table 1.
Summary of VEP responses in WT and Ten-m2 KO mice
| Visual presentation | AUCa (μV*ms) | Peakb-to-troughc magnitude (μV) | Peak slope (μV/ms) | Peak magnitude (μV) | Time-to-peak (ms) | Peak-to-trough slope (μV/ms) | Trough magnitude (μV) | Time-to-trough (ms) |
|---|---|---|---|---|---|---|---|---|
| Binocular | ||||||||
| WT | 2233 ± 444 | 298.8 ± 38.9 | 56.9 ± 9.3 | 173.0 ± 20.5 | 21.5 ± 0.8 | −46.3 ± 13.8 | −125.8 ± 19.4 | 33.2 ± 1.9 |
| Ten-m2 KO | 1258 ± 249 | 204.6 ± 8.8* | 26.4 ± 4.2* | 107.2 ± 8.9* | 22.3 ± 1.6 | −18.0 ± 4.6 | −97.3 ± 8.4 | 36.6 ± 3.3 |
| Contralateral | ||||||||
| WT | 1431 ± 389 | 242.2 ± 40.3 | 51.4 ± 9.3 | 133.1 ± 20.5 | 20.0 ± 0.6 | −39.8 ± 12.2 | −109.1 ± 20.6 | 32.7 ± 3.6 |
| Ten-m2 KO | 1217 ± 313 | 193.9 ± 18.9 | 30.7 ± 8.4 | 112.0 ± 17.2 | 22.5 ± 1.2 | −19.8 ± 8.4 | −81.8 ± 7.0 | 39.0 ± 4.9 |
| Ipsilateral | ||||||||
| WT | 1249 ± 256 | 189.3 ± 26.9 | 24.8 ± 4.0 | 92.8 ± 12.2 | 22.1 ± 1.0 | −24.0 ± 6.7 | −96.5 ± 17.6 | 34.2 ± 2.1 |
| Ten-m2 KO | 452 ± 176* | 114.5 ± 16.6* | 29.0 ± 10.3 | 57.0 ± 9.2* | 24.2 ± 3.5 | −9.5 ± 4.4 | −57.5 ± 8.9 | 40.7 ± 4.6 |
VEP data presented as mean ± SEM. Asterisk indicates significant differences (p < 0.05, Student's unpaired t test) in Ten-m2 KO responses (n = 6) compared to WT (n = 10).
aAUC was calculated over the whole response.
bPeak refers to the maximum of the major positive component of each response.
cTrough refers to the minimum of the negative component.