Figure 7.

R-type VDCCs are not expressed at the soma of L5 pyramidal neurons. A, Layer 5 pyramidal neuron filled with OGB-1. The black and yellow boxes indicate somatic and dendritic regions of interest for point scans, the results of which are shown in B. Scale bar, 35 μm. B, Point scans of regions shown in A during a single AP before and after wash-in of SNX 482. Solid line and shaded regions represent the mean ± SEM. C, Average peak ΔF/F for the soma and dendrite before and after wash-in of SNX 482 (±SEM; n = 5). D, Average percentage change in fluorescence transients after wash-in of SNX 482 for the soma and dendrite (±SEM; n = 5). **p < 0.01, ns, Not significant.