Figure 6.
Frequency-dependent contribution of Ih, but not INaP, to respiratory rhythm. Relationship between baseline frequency while microperfusing aCSF into the preBötC and the changes elicited by the Ih blocker ZD7288 or the INaP blocker riluzole. A, B, There was a significant correlation between baseline frequency and the capacity of ZD7288 to reduce respiratory frequency (n = 7). 95% confidence interval is indicated by gray areas. C, D, No significant correlation was found while comparing baseline frequency and blockade by riluzole (n = 7).